Description

Spiro[Cyclopropane-1,8(5H)-Indolizine]-3,7(2H,6H)-Dione, Dihydro-1,2-Dihydroxy- (9Ci) is a complex spirocyclic organic compound featuring a fused indolizine-dione structure with dihydroxycyclopropane functionality. This compound serves as a high-value synthetic intermediate and building block in advanced organic synthesis, prized for its unique three-dimensional architecture. It is primarily utilized by pharmaceutical R&D and fine chemical sectors for the development of novel active ingredients and complex molecular scaffolds.

Application

This specialized chemical intermediate enables sophisticated synthetic pathways across several high-tech industries.

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring complex stereochemistry.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides with unique modes of action.
• Material Science: Serves as a precursor for advanced organic electronic materials or specialty polymers.
• Academic & Contract Research: Employed in methodological studies and the discovery of new chemical reactions (e.g., cycloadditions, cascade transformations).
• Asymmetric Synthesis: The chiral dihydroxycyclopropane moiety makes it a valuable substrate for catalytic asymmetric transformations.

Basic Information

Item	Details
Product Name	Spiro[Cyclopropane-1,8(5H)-Indolizine]-3,7(2H,6H)-Dione, Dihydro-1,2-Dihydroxy- (9Ci)
CAS No.	383909-08-8
Molecular Formula	C11H11NO4
Molecular Weight	221.21 g/mol
Synonyms	1,2-Dihydroxy-1,2-dihydrospiro[cyclopropane-1,8'(5'H)-indolizine]-3',7'-dione; Dihydro-1,2-dihydroxyspiro[cyclopropane-1,8(5H)-indolizine]-3,7(2H,6H)-dione; Spiro[cyclopropane-1,8-indolizine]-3,7-dione, dihydro-1,2-dihydroxy-; 383909-08-8; Spirocyclopropane-indolizinedione derivative
EINECS	Contact for details

Quality Control

Our production of Spiro[Cyclopropane-1,8(5H)-Indolizine]-3,7(2H,6H)-Dione, Dihydro-1,2-Dihydroxy- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and purity for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support cGMP compliance for advanced intermediates and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.