Description

(2E)-3-(4-Fluoro-3-Nitrophenyl)-2-Propenoic Acid, Ethyl Ester is a high-purity, synthetic organic intermediate characterized by its conjugated ester structure and substituted aromatic ring. This compound is of significant commercial value as a versatile building block in advanced pharmaceutical synthesis and fine chemical manufacturing. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and inflammatory conditions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and fungicides, leveraging the fluoronitrophenyl moiety for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic semiconductors, nonlinear optical (NLO) materials, and advanced polymers due to its electron-withdrawing groups and planar structure.
• Chemical Biology Probes: Utilized in the design and synthesis of fluorescent tags and molecular probes for diagnostic and research applications.

Basic Information

Product Name	(2E)-3-(4-Fluoro-3-Nitrophenyl)-2-Propenoic Acid, Ethyl Ester
CAS No.	383664-94-6
Molecular Formula	C11H10FNO4
Molecular Weight	239.20 g/mol
Synonyms	Ethyl (2E)-3-(4-Fluoro-3-nitrophenyl)acrylate; Ethyl (E)-3-(4-Fluoro-3-nitrophenyl)propenoate; (E)-Ethyl 3-(4-Fluoro-3-nitrophenyl)acrylate; 4-Fluoro-3-nitrocinnamic Acid Ethyl Ester; (E)-3-(4-Fluoro-3-nitrophenyl)acrylic Acid Ethyl Ester; 383664-94-6; Ethyl 4-Fluoro-3-nitrocinnamate; NSC 405124
EINECS	Contact for details

Quality Control

Our production of (2E)-3-(4-Fluoro-3-Nitrophenyl)-2-Propenoic Acid, Ethyl Ester adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our quality commitment supports compliance with cGMP and ISO standards for pharmaceutical and fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.