Description

1,6-Naphthyridine-3-Carboxylic Acid, 4-Cyano-6-Ethyl-1,2,5,6,7,8-Hexahydro-2-Thioxo-, Ethyl Ester is a sophisticated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its unique naphthyridine-thioxo scaffold.
• Ligand Synthesis: Acts as a starting material for creating complex chelating ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Advanced Material Development: Potential use in the synthesis of organic electronic materials due to its conjugated system and functional groups.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic projects requiring this specialized scaffold.

Basic Information

Item	Details
Product Name	1,6-Naphthyridine-3-Carboxylic Acid, 4-Cyano-6-Ethyl-1,2,5,6,7,8-Hexahydro-2-Thioxo-, Ethyl Ester
CAS No.	382640-58-6
Molecular Formula	C15H17N3O2S
Molecular Weight	303.38 g/mol
Synonyms	Ethyl 4-cyano-6-ethyl-2-thioxo-1,2,5,6,7,8-hexahydro-1,6-naphthyridine-3-carboxylate; 4-Cyano-6-ethyl-2-thioxo-1,2,5,6,7,8-hexahydro-1,6-naphthyridine-3-carboxylic acid ethyl ester; 6-Ethyl-4-cyano-2-thioxo-1,2,5,6,7,8-hexahydro-1,6-naphthyridine-3-carboxylic acid ethyl ester; 1,2,5,6,7,8-Hexahydro-4-cyano-6-ethyl-2-thioxo-1,6-naphthyridine-3-carboxylic acid ethyl ester; 382640-58-6; SCHEMBL2184227
EINECS	Contact for details

Quality Control

Our 1,6-Naphthyridine-3-Carboxylic Acid, 4-Cyano-6-Ethyl-1,2,5,6,7,8-Hexahydro-2-Thioxo-, Ethyl Ester is produced under a strict quality management system. Each batch undergoes comprehensive analytical characterization including HPLC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.