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D-Galactose 1-[2-(2-Azidoethoxy)Ethoxyethyl]-2,3,4,6-Tetra-o-Acetate CAS NO 381716-33-2


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CAS No.:381716-33-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

D-Galactose 1-[2-(2-Azidoethoxy)Ethoxyethyl]-2,3,4,6-Tetra-o-Acetate is a sophisticated, acetyl-protected galactose derivative featuring a polyethylene glycol (PEG)-based linker terminated with an azide functional group. This compound is engineered for high-value applications in chemical biology and pharmaceutical research, serving as a critical building block for the synthesis of complex glycoconjugates. It is primarily utilized by researchers and process development scientists in the fields of bioconjugation, click chemistry, and carbohydrate-based drug discovery.

Application

  • Click Chemistry Reagent: The terminal azide group enables efficient, copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for labeling and conjugating biomolecules.
  • Glycoconjugate Synthesis: Acts as a key intermediate for constructing neoglycoproteins, glycopolymers, and other complex carbohydrate structures for biological studies.
  • Bioconjugation Linker: The PEG spacer enhances solubility and provides a flexible tether for attaching galactose motifs to surfaces, nanoparticles, or therapeutic proteins.
  • Pharmaceutical Intermediates: Used in the research and development of targeted drug delivery systems and diagnostic agents that exploit carbohydrate-receptor interactions.
  • Chemical Probe Development: Facilitates the creation of probes for studying galectin biology, carbohydrate metabolism, and cell-surface interactions.
  • Material Science: Serves as a functional monomer or cross-linker for creating bioactive hydrogels and smart materials with specific carbohydrate recognition properties.

Basic Information

Product Name D-Galactose 1-[2-(2-Azidoethoxy)Ethoxyethyl]-2,3,4,6-Tetra-o-Acetate
CAS No. 381716-33-2
Molecular Formula C22H35N3O12
Molecular Weight 533.53 g/mol
Synonyms 1-O-[2-[2-(2-Azidoethoxy)ethoxy]ethyl]-2,3,4,6-tetra-O-acetyl-β-D-galactopyranoside; 2,3,4,6-Tetra-O-acetyl-β-D-galactopyranosyl 2-[2-(2-azidoethoxy)ethoxy]ethyl ether; Ac4Galβ-O-(CH2CH2O)2CH2CH2N3; Galactose tetraacetate azido-PEG2 derivative; Azido-PEG2-β-D-Galactose tetraacetate; β-D-Galactopyranoside, 2,3,4,6-tetraacetate, 1-O-[2-[2-(2-azidoethoxy)ethoxy]ethyl]-
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Quality Control

Our production of this advanced biochemical intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive research applications. Identity and purity are confirmed through a suite of analytical techniques including NMR (1H, 13C), HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Allow the product to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item Specification
Appearance White to off-white solid or viscous oil
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95%
Water Content (KF) ≤ 0.5%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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