Description

Benzenepropanoic Acid,A-[(1,3-Dihydro-1,3-Dioxo-2H-Isoindol-2-Yl)Oxy]-, 1,1-Dimethylethyl Ester, (Ar)- is a specialized chiral intermediate of significant importance in advanced organic synthesis. This compound matters because it provides a protected, reactive handle for constructing complex molecules with high stereochemical fidelity. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of chiral drug candidates and complex therapeutic molecules.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or protected synthon in stereoselective chemical reactions.
• Peptidomimetics Research: Serves as a precursor for introducing specific functional groups into peptide-like structures.
• Agrochemical Development: Intermediate in the research and production of advanced, optically active crop protection agents.
• Material Science: Potential monomer or modifier in the synthesis of specialized polymers with targeted properties.
• Academic & R&D: Used in university and corporate laboratories for methodological development in organic chemistry.

Basic Information

Item	Details
Product Name	Benzenepropanoic Acid,A-[(1,3-Dihydro-1,3-Dioxo-2H-Isoindol-2-Yl)Oxy]-, 1,1-Dimethylethyl Ester, (Ar)-
CAS No.	380886-37-3
Molecular Formula	C21H21NO5
Molecular Weight	367.40 g/mol
Synonyms	(R)-2-((1,3-Dioxoisoindolin-2-yl)oxy)-3-phenylpropanoic acid tert-butyl ester; tert-Butyl (R)-2-((1,3-dioxoisoindolin-2-yl)oxy)-3-phenylpropanoate; (R)-N-Phthaloyl-3-phenylalanine tert-butyl ester; (R)-2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yloxy)-3-phenyl-propionic acid tert-butyl ester; (R)-2-Phthalimido-3-phenylpropionic acid tert-butyl ester; (Ar)-Benzenepropanoic acid, α-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)oxy]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our Benzenepropanoic Acid,A-[(1,3-Dihydro-1,3-Dioxo-2H-Isoindol-2-Yl)Oxy]-, 1,1-Dimethylethyl Ester, (Ar)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting research and pharmaceutical-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.