Description

Ethyl [3-(Trifluoromethyl)-1H-Pyrazol-1-Yl]Acetate is a high-value fluorinated pyrazole derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in the trifluoromethyl group, which imparts unique physicochemical properties essential for developing compounds with enhanced metabolic stability and bioavailability. This product is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals that require fluorinated components for specific thermal or optical properties.
• Chemical Biology Probes: Employed in the creation of tagged molecules for studying enzyme mechanisms and protein interactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for fine chemical manufacturers offering bespoke synthesis services to the life sciences sector.

Basic Information

Product Name	Ethyl [3-(Trifluoromethyl)-1H-Pyrazol-1-Yl]Acetate
CAS No.	380872-50-4
Molecular Formula	C8H9F3N2O2
Molecular Weight	222.17 g/mol
Synonyms	Ethyl 2-[3-(trifluoromethyl)-1H-pyrazol-1-yl]acetate; 1H-Pyrazole-1-acetic acid, 3-(trifluoromethyl)-, ethyl ester; Ethyl (3-trifluoromethyl-1H-pyrazol-1-yl)acetate; 380872-50-4; Acetic acid, 2-[3-(trifluoromethyl)-1H-pyrazol-1-yl]-, ethyl ester
EINECS	Contact for details

Quality Control

Our production of Ethyl [3-(Trifluoromethyl)-1H-Pyrazol-1-Yl]Acetate adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every shipment, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.