Description

Methyl 3-{[3-Chloro-5-(Trifluoromethyl)Pyridin-2-Yl]Thio}Propanoate is a high-value, multi-functional chemical intermediate characterized by its unique pyridine-thioether-ester structure. This compound is critical for advanced synthesis, particularly in the development of novel active ingredients for the agrochemical and pharmaceutical sectors. It is primarily sought by R&D chemists and process development teams in fine chemical manufacturing for constructing complex molecules with specific biological activities.

Application

• Agrochemical Intermediate: A key building block for the synthesis of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the chlorotrifluoromethylpyridine moiety.
• Pharmaceutical Research: Serves as a versatile synthon in medicinal chemistry for creating potential drug candidates, especially in libraries targeting enzyme inhibition.
• Ligand & Catalyst Precursor: Used in the development of specialized ligands for metal-catalyzed cross-coupling reactions due to the sulfur and nitrogen donor atoms.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific electronic or surface properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for proprietary client synthesis projects.

Basic Information

Product Name	Methyl 3-{[3-Chloro-5-(Trifluoromethyl)Pyridin-2-Yl]Thio}Propanoate
CAS No.	380453-90-7
Molecular Formula	C10H9ClF3NO2S
Molecular Weight	299.69 g/mol
Synonyms	Methyl 3-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)propanoate; 2-Pyridinepropanoic acid, 3-chloro-5-(trifluoromethyl)-, 3-thioxo-, methyl ester; Methyl 3-[(3-chloro-5-trifluoromethyl-2-pyridyl)thio]propionate; Propanoic acid, 3-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]thio]-, methyl ester; 380453-90-7
EINECS	Contact for details

Quality Control

Our production of Methyl 3-{[3-Chloro-5-(Trifluoromethyl)Pyridin-2-Yl]Thio}Propanoate adheres to stringent in-process controls and final batch analysis to ensure consistent purity and identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality system is designed to meet the exacting standards of fine chemical and pharmaceutical intermediate supply, ensuring reliable performance in your critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after opening the original container. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.