Description

2-Furancarboxylicacid,Tetrahydro-,Ethylester,(2S)-(9Ci) is a chiral, non-racemic ester derivative of tetrahydrofuran-2-carboxylic acid, serving as a valuable synthetic intermediate and building block in advanced organic synthesis. Its defined stereochemistry at the 2-position makes it particularly significant for the production of enantiomerically pure pharmaceuticals and fine chemicals. This high-purity intermediate is essential for research and development laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate chiral tetrahydrofuran motifs.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), especially those containing tetrahydrofuran rings.
• Asymmetric Synthesis: Used as a starting material or chiral auxiliary in stereoselective reactions to construct complex molecular architectures.
• Agrochemical Research: Intermediate in the development of novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Flavor & Fragrance Industry: Potential precursor for the synthesis of specific lactones and flavor compounds.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands used in transition metal catalysis.
• Academic & Industrial R&D: Critical reagent for methodological development in organic chemistry and process chemistry optimization.

Basic Information

Product Name	2-Furancarboxylicacid,Tetrahydro-,Ethylester,(2S)-(9Ci)
CAS No.	375825-10-8
Molecular Formula	C7H12O3
Molecular Weight	144.17 g/mol
Synonyms	(2S)-Tetrahydrofuran-2-carboxylic acid ethyl ester; Ethyl (2S)-tetrahydro-2-furoate; (S)-Tetrahydro-2-furancarboxylic acid ethyl ester; (S)-Ethyl tetrahydro-2-furoate; (2S)-2-Carbethoxy-tetrahydrofuran; Ethyl (S)-(-)-tetrahydro-2-furoate; Tetrahydro-2-furancarboxylic acid, ethyl ester, (2S)-; (S)-(-)-Ethyl tetrahydro-2-furancarboxylate
EINECS	Contact for details

Quality Control

Our production of (2S)-Tetrahydrofuran-2-carboxylic acid ethyl ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized by comprehensive analytical methods including chiral HPLC to confirm enantiomeric excess (ee) and GC/HPLC for purity assessment. A Certificate of Analysis (COA) detailing identity, purity, assay, and specific rotation is provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to prevent moisture absorption or contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.