Description

Ethyl 34Difluorocinnamate is a high-purity fluorinated cinnamate derivative, a key synthetic intermediate prized for its unique chemical reactivity. Its molecular structure, featuring both the cinnamate ester moiety and strategically placed fluorine atoms, makes it an essential building block for advanced organic synthesis. This compound is primarily sought after by research institutions and industrial R&D teams in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated drug candidates, particularly in oncology and CNS therapeutic areas, where fluorine substitution can enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of next-generation pesticides and herbicides, leveraging the fluorinated aromatic ring to improve lipophilicity and target binding.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated mesogens and electron-transport materials, contributing to improved performance in display and lighting technologies.
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart specific properties such as enhanced chemical resistance, lower surface energy, or altered refractive index.
• Organic Synthesis & Catalysis Research: Employed in academic and industrial labs for studying cross-coupling reactions, photochemical transformations, and as a ligand precursor in organometallic chemistry.
• Flavor & Fragrance Intermediate: Used in the controlled synthesis of complex aromatic esters for high-value fragrance and flavor compounds.

Basic Information

Product Name	Ethyl 34Difluorocinnamate
CAS No.	375368-92-6
Molecular Formula	C11H10F2O2
Molecular Weight	212.19 g/mol
Synonyms	Ethyl 3,4-Difluorocinnamate; 3,4-Difluorocinnamic Acid Ethyl Ester; (E)-Ethyl 3-(3,4-difluorophenyl)acrylate; 2-Propenoic acid, 3-(3,4-difluorophenyl)-, ethyl ester; Ethyl (E)-3-(3,4-difluorophenyl)acrylate; NSC 79514; AI3-32936
EINECS	Contact for details

Quality Control

Our Ethyl 34Difluorocinnamate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets stringent specifications for research and industrial use. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong alkalis and fluorides. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.