Description

9'-Bromo-1-Methyl-2'-Phenyl-1',10'B-Dihydrospiro(Piperidine-4,5'-Pyrazolo[1,5-C][1,3]Benzoxazine) is a sophisticated spirocyclic organic compound featuring a complex heterocyclic architecture, making it a valuable and versatile advanced pharmaceutical intermediate. Its unique molecular framework is specifically engineered for high-value synthesis, offering researchers and manufacturers a critical building block for developing novel active ingredients. This compound is primarily targeted at pharmaceutical R&D and fine chemical synthesis sectors, where precision and molecular complexity are paramount.

Application

This high-purity intermediate is designed for specialized chemical synthesis, with key applications including:

• Pharmaceutical Intermediate: Serving as a critical precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and library synthesis.
• Organic Synthesis Reagent: Employed in complex multi-step syntheses to construct intricate heterocyclic systems.
• Chemical Biology Probe Development: Utilized in the creation of molecular probes for studying biological pathways and target validation.
• Process Chemistry Development: Applied in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).

Basic Information

Item	Details
Product Name	9'-Bromo-1-Methyl-2'-Phenyl-1',10'B-Dihydrospiro(Piperidine-4,5'-Pyrazolo[1,5-C][1,3]Benzoxazine)
CAS No.	374921-75-2
Molecular Formula	C21H20BrN3O
Molecular Weight	410.31 g/mol
Synonyms	9'-Bromo-1-methyl-2'-phenyl-1',10'b-dihydrospiro[piperidine-4,5'-pyrazolo[1,5-c][1,3]benzoxazine]; 1',10'B-Dihydro-9'-bromo-1-methyl-2'-phenylspiro[piperidine-4,5'-pyrazolo[1,5-c][1,3]benzoxazine]; Spiro[piperidine-4,5'-pyrazolo[1,5-c][1,3]benzoxazine], 9'-bromo-1',10'b-dihydro-1-methyl-2'-phenyl-; 374921-75-2; 9'-Bromo-1-methyl-2'-phenyl-1',10'b-dihydrospiro(piperidine-4,5'-pyrazolo[1,5-c][1,3]benzoxazine)
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for your critical syntheses. We provide comprehensive analytical data, including HPLC purity and spectroscopic identification (NMR, MS). A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with every batch. Our quality system is designed to support cGMP and ISO standards for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be sensitive to moisture and should be handled under an inert atmosphere for long-term storage to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.