Description

(4-Oxo-1-Phenyl-Cyclohexyl)-Carbamic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its unique cyclohexanone and carbamate functional groups. This compound is critical for the synthesis of complex organic molecules, offering a protected amine handle and a ketone moiety for further derivatization. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the multi-step synthesis of potential drug candidates, particularly in medicinal chemistry research.
• Organic Synthesis Reagent: Used in academic and industrial laboratories for constructing complex molecular architectures, leveraging its tert-butyloxycarbonyl (Boc) protected amine.
• Protease Inhibitor Research: Acts as a precursor or core structure in the development of enzyme inhibitors targeting various disease pathways.
• Chemical Biology Probes: Utilized in the creation of specialized probes and ligands for studying biological processes and target identification.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds under cGMP conditions.

Basic Information

Product Name	(4-Oxo-1-Phenyl-Cyclohexyl)-Carbamic Acid tert-Butyl Ester
CAS No.	374796-10-8
Molecular Formula	C₁₇H₂₃NO₃
Molecular Weight	289.37 g/mol
Synonyms	1-Phenyl-4-oxocyclohexyl carbamic acid tert-butyl ester; tert-Butyl N-(1-phenyl-4-oxocyclohexyl)carbamate; Boc-4-oxo-1-phenyl-cyclohexylamine; (1-Phenyl-4-oxocyclohexyl)carbamic acid 1,1-dimethylethyl ester; 4-Oxo-1-phenylcyclohexylamine N-Boc derivative; N-Boc-1-phenyl-4-oxocyclohexylamine; N-(tert-Butoxycarbonyl)-1-phenyl-4-oxocyclohexylamine
EINECS	Contact for details

Quality Control

Our (4-Oxo-1-Phenyl-Cyclohexyl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.