Description

2-Oxa-9-Azaspiro[5.5]Undecane-9-Carboxylic Acid, 1,1-Dimethylethyl Ester is a high-value, protected heterocyclic building block used in advanced organic synthesis. This compound is critical for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of spirocyclic and bridged heterocyclic compounds with potential biological activity.
• Medicinal Chemistry Research: Used in the discovery and optimization of new drug candidates, particularly for central nervous system (CNS) and other therapeutic targets.
• Process Chemistry Development: Serves as a starting material or advanced intermediate in the scalable synthesis of active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Employed in the research and development of novel pesticides and herbicides requiring complex heterocyclic cores.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological studies and the creation of proprietary chemical libraries.
• Fine Chemical Production: Intermediate for the manufacture of specialty chemicals, catalysts, and ligands used in asymmetric synthesis.

Basic Information

Product Name	2-Oxa-9-Azaspiro[5.5]Undecane-9-Carboxylic Acid, 1,1-Dimethylethyl Ester
CAS No.	374795-47-8
Molecular Formula	C13H23NO3
Molecular Weight	241.33 g/mol
Synonyms	tert-Butyl 2-oxa-9-azaspiro[5.5]undecane-9-carboxylate; 9-Boc-2-oxa-9-azaspiro[5.5]undecane; 2-Oxa-9-azaspiro[5.5]undecane-9-carboxylic acid tert-butyl ester; Boc-2-oxa-9-azaspiro[5.5]undecane; 1,1-Dimethylethyl 2-oxa-9-azaspiro[5.5]undecane-9-carboxylate; 9-(tert-Butoxycarbonyl)-2-oxa-9-azaspiro[5.5]undecane; Spirocyclic Boc-protected amine ether
EINECS	Contact for details

Quality Control

Our 2-Oxa-9-Azaspiro[5.5]Undecane-9-Carboxylic Acid, 1,1-Dimethylethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.