Description

1-Oxa-9-Azaspiro[5.5]Undec-3-Ene-9-Carboxylic Acid, 1,1-Dimethylethyl Ester is a high-value, protected heterocyclic building block essential for advanced organic synthesis. This compound is specifically engineered to serve as a key intermediate in the development of complex pharmaceutical molecules and bioactive compounds. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with spirocyclic or bridged heterocyclic frameworks.
• Medicinal Chemistry Research: Used in drug discovery programs for building diverse compound libraries and exploring new chemical space for biological activity.
• Agrochemical Synthesis: Serves as a building block for developing novel pesticides and herbicides with specific modes of action.
• Fine Chemical Production: Employed in the multi-step synthesis of complex specialty chemicals, flavors, and fragrances.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic synthesis, including novel cyclization and functionalization reactions.

Basic Information

Product Name	1-Oxa-9-Azaspiro[5.5]Undec-3-Ene-9-Carboxylic Acid, 1,1-Dimethylethyl Ester
CAS No.	374795-40-1
Molecular Formula	C13H21NO3
Molecular Weight	239.31 g/mol
Synonyms	tert-Butyl 1-oxa-9-azaspiro[5.5]undec-3-ene-9-carboxylate; 9-Boc-1-oxa-9-azaspiro[5.5]undec-3-ene; 1-Oxa-9-azaspiro[5.5]undec-3-ene-9-carboxylic acid tert-butyl ester; Boc-1-oxa-9-azaspiro[5.5]undec-3-ene; 374795-40-1; tert-Butyl 9-azaspiro[5.5]undec-3-ene-9-carboxylate 1-oxide (related); Bicyclic Boc-protected amine
EINECS	Contact for details

Quality Control

Our production of 1-Oxa-9-Azaspiro[5.5]Undec-3-Ene-9-Carboxylic Acid, 1,1-Dimethylethyl Ester adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or manufacturing standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.