Description

1-Oxa-8-Azaspiro[4.5]Decan-2-One Hydrochloride is a high-purity, heterocyclic organic compound featuring a unique spirocyclic structure, making it a valuable synthetic intermediate. This compound is critical for research and development in advanced pharmaceutical chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS).
• Organic Synthesis Reagent: Used in advanced organic chemistry for constructing complex spirocyclic and heterocyclic frameworks.
• Medicinal Chemistry Research: Serves as a crucial scaffold for structure-activity relationship (SAR) studies in drug discovery programs.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
• Precursor for Specialty Chemicals: Used in the development of specialty fine chemicals with specific biological or material properties.

Basic Information

Product Name	1-Oxa-8-Azaspiro[4.5]Decan-2-One Hydrochloride
CAS No.	374794-92-0
Molecular Formula	C8H14ClNO2
Molecular Weight	191.66 g/mol
Synonyms	8-Aza-1-oxaspiro[4.5]decan-2-one hydrochloride; 1-Oxa-8-azaspiro[4.5]decan-2-one, hydrochloride; 1-Oxa-8-azaspiro[4.5]decan-2-one HCl; Spirocyclic lactam hydrochloride; Tetrahydro-2H-1,4-oxazepin-5(3H)-one, hexahydro-, hydrochloride; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 1-Oxa-8-Azaspiro[4.5]Decan-2-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.