Description

Carbamic Acid, [(2R,3E)-2-Methyl-3-Hexen-5-Ynyl]-, 1,1-Dimethylethyl Ester is a specialized chiral building block featuring a unique combination of an alkyne and an alkene functional group within its molecular framework. This compound is valued for its role as a key synthetic intermediate in the production of complex, biologically active molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, asymmetric synthesis, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new drug candidates, particularly in constructing complex molecular architectures.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and the synthesis of targeted libraries for high-throughput screening.
• Agrochemical Synthesis: Serves as a building block in the development of advanced pesticides, herbicides, or fungicides with specific stereochemical requirements.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development of new catalytic systems for stereoselective transformations.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes due to its reactive alkyne handle for click chemistry applications like CuAAC.
• Advanced Material Precursors: Potential use in synthesizing specialized monomers or ligands for polymeric or supramolecular materials.

Basic Information

Item	Details
Product Name	Carbamic Acid, [(2R,3E)-2-Methyl-3-Hexen-5-Ynyl]-, 1,1-Dimethylethyl Ester
CAS No.	374729-51-8
Molecular Formula	C14H21NO2
Molecular Weight	235.32 g/mol
Synonyms	tert-Butyl (2R,3E)-2-methyl-3-hexen-5-yn-1-ylcarbamate; (R,E)-tert-Butyl (2-methylhex-3-en-5-yn-1-yl)carbamate; N-Boc-(2R,3E)-2-Methyl-3-hexen-5-yn-1-amine; Boc-(2R,3E)-2-Methyl-3-hexen-5-ynylamine; (2R,3E)-2-Methyl-3-hexen-5-yn-1-amine, N-Boc derivative; Chiral Alkenyl Alkyne Boc-Amine
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, [(2R,3E)-2-Methyl-3-Hexen-5-Ynyl]-, 1,1-Dimethylethyl Ester adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and enantiomeric purity suitable for advanced synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to maintain stability and prevent oxidation. Keep the container in a cool, dry, and well-ventilated area, separate from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.