Description

2-Nitrodeamino Fingolimod is a key synthetic intermediate and derivative of the immunomodulatory drug Fingolimod. This compound is of significant value in pharmaceutical research and development, particularly for the synthesis of novel analogs and for conducting structure-activity relationship (SAR) studies. It is primarily utilized by pharmaceutical companies, contract research organizations (CROs), and academic laboratories engaged in the development of next-generation S1P receptor modulators for treating autoimmune and inflammatory diseases.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of Fingolimod analogs and related sphingosine-1-phosphate (S1P) receptor modulators.
• Research & Development: Used in medicinal chemistry programs for structure-activity relationship (SAR) studies to optimize drug efficacy and safety profiles.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in API manufacturing.
• Process Chemistry: Employed in route scouting and scale-up optimization for the production of advanced pharmaceutical intermediates.
• Biochemical Research: Tool compound for investigating the S1P signaling pathway and its role in immunology and neurology.

Basic Information

Product Name	2-Nitrodeamino Fingolimod
CAS No.	374077-88-0
Molecular Formula	C19H33N2O5P
Molecular Weight	400.45 g/mol
Synonyms	2-Nitro-FTY720; 2-Nitro-2-amino-2-(2-(4-octylphenyl)ethyl)propane-1,3-diol 1-(Dihydrogen Phosphate); FTY720 2-Nitro Analog; 2-Nitrodeamino-Fingolimod; (2-Nitro-2-{[2-(4-octylphenyl)ethyl]amino}propane-1,3-diyl) Dihydrogen Phosphate; 2-Nitroamino-FTY720 Derivative
EINECS	Contact for details

Quality Control

Our 2-Nitrodeamino Fingolimod is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent control of residual solvents and impurities. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.