Description

(2R)-1,3-Oxathiolan-2-Ylmethyl Benzoate CAS NO 372112-46-4 is a high-purity chiral building block and pharmaceutical intermediate of significant synthetic value. Its defined stereochemistry and functionalized oxathiolane core make it a critical precursor in the development of enantiomerically pure active pharmaceutical ingredients (APIs). This compound is essential for research and manufacturing chemists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of nucleoside analogs and other enantiomerically pure therapeutic agents.
• Asymmetric Synthesis: Used as a building block in stereoselective chemical reactions to construct complex molecular architectures.
• Agrochemical Research: Serves as a precursor in the development of chiral pesticides and herbicides with enhanced efficacy and selectivity.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic chemistry and catalysis studies.
• Process Chemistry: Used in scale-up and optimization of synthetic routes for commercial API production.

Basic Information

Product Name	(2R)-1,3-Oxathiolan-2-Ylmethyl Benzoate
CAS No.	372112-46-4
Molecular Formula	C11H12O3S
Molecular Weight	224.27 g/mol
Synonyms	(R)-1,3-Oxathiolan-2-Ylmethyl Benzoate; (2R)-2-(Hydroxymethyl)-1,3-oxathiolane Benzoate; Benzoic Acid (2R)-1,3-Oxathiolan-2-Ylmethyl Ester; (R)-Oxathiolane Methyl Benzoate; (2R)-Oxathiolanyl Methyl Benzoate; (R)-OTM Benzoate; Chiral Oxathiolane Benzoate Ester
EINECS	Contact for details

Quality Control

Our (2R)-1,3-Oxathiolan-2-Ylmethyl Benzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.