Description

Spiro[2.4]Heptane-1,4-Dicarboxylic Acid, 4-Amino-, (4R)- (9Ci) is a high-purity, chiral spirocyclic compound serving as a sophisticated building block in advanced organic synthesis. Its unique constrained spiro structure and bifunctional amino-diacid chemistry make it a valuable intermediate for constructing complex molecular architectures with precise stereochemistry. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and chiral ligands.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the creation of advanced, stereospecific herbicides, fungicides, and plant growth regulators.
• Chiral Catalyst & Ligand Precursor: Serves as a foundational structure for synthesizing novel chiral catalysts and ligands used in asymmetric synthesis.
• Advanced Material Research: Employed in the development of specialty polymers and organic frameworks with unique structural and optical properties.
• Peptidomimetics & Conformationally Restricted Peptides: The spiro scaffold is utilized to design and synthesize peptide analogs with enhanced metabolic stability and biological activity.
• Chemical Biology & Probe Development: Acts as a versatile handle for creating molecular probes to study enzyme function and biological pathways.

Basic Information

Item	Details
Product Name	Spiro[2.4]Heptane-1,4-Dicarboxylic Acid, 4-Amino-, (4R)- (9Ci)
CAS No.	371980-02-8
Molecular Formula	C10H13NO4
Molecular Weight	211.21 g/mol
Synonyms	(4R)-4-Aminospiro[2.4]heptane-1,4-dicarboxylic acid; 4-Aminospiro[2.4]heptane-1,4-dicarboxylic acid, (4R)-; 1,4-Dicarboxy-4-aminospiro[2.4]heptane; (4R)-1,4-Dicarboxy-4-aminospiro[2.4]heptane; Spiro[2.4]heptane-1,4-dicarboxylic acid, 4-amino-, (4R)-; (R)-4-Amino-spiro[2.4]heptane-1,4-dicarboxylic acid; 371980-02-8; (4R)-4-Amino-1,4-dicarboxyspiro[2.4]heptane
EINECS	Contact for details

Quality Control

Every batch of Spiro[2.4]Heptane-1,4-Dicarboxylic Acid, 4-Amino-, (4R)- (9Ci) is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity consistent with research and development standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.