Description

Spiro[2.4]Heptane-1,4-Dicarboxylic Acid, 4-Amino-, (4S)- (9Ci) is a high-value, chiral spirocyclic compound serving as a sophisticated building block in advanced organic synthesis. Its unique constrained three-dimensional structure and bifunctional nature make it a critical intermediate for developing novel pharmaceuticals and specialty materials. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to create complex molecules with enhanced biological activity or specific physical properties.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug discovery.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, where its spirocyclic core can impart unique biological activity and stability.
• Ligand & Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: A building block for advanced polymers and specialty chemicals requiring rigid, three-dimensional molecular architectures.
• Academic & Industrial R&D: Employed in research laboratories for methodological studies in organic chemistry and the exploration of new chemical spaces.

Basic Information

Product Name	Spiro[2.4]Heptane-1,4-Dicarboxylic Acid, 4-Amino-, (4S)- (9Ci)
CAS No.	371980-01-7
Molecular Formula	C10H13NO4
Molecular Weight	211.21 g/mol
Synonyms	(4S)-4-Aminospiro[2.4]heptane-1,4-dicarboxylic acid; (1S,4S)-4-Amino-1-carboxyspiro[2.4]heptane-1-carboxylic acid; 4-Aminospiro[2.4]heptane-1,4-dicarboxylic acid, (4S)-; Spiro[2.4]heptane-1,4-dicarboxylic acid, 4-amino-, (4S)-; 371980-01-7; (S)-4-Aminospiro[2.4]heptane-1,4-dicarboxylic acid
EINECS	Contact for details

Quality Control

Our production of Spiro[2.4]Heptane-1,4-Dicarboxylic Acid, 4-Amino-, (4S)- (9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.