Description

2-Oxo-4-Trifluoromethyl-2,5,6,7-Tetrahydro-1H-[1]Pyridindine-3-Carbonitrile is a high-value, heterocyclic organic compound featuring a fused pyridine-dione structure with a strategically positioned trifluoromethyl group and nitrile functionality. This molecular architecture makes it a critical advanced pharmaceutical intermediate for the synthesis of novel active ingredients. It is primarily sought after by R&D and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, particularly in central nervous system (CNS) and metabolic disorder therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances bioactivity and environmental stability.
• Material Science Research: Serves as a precursor for novel organic electronic materials or ligands for catalytic systems due to its electron-withdrawing substituents.
• Chemical Biology Probe Development: Utilized in creating tool compounds for studying enzyme function and biological pathways in academic and industrial research.
• Custom Synthesis & Contract Manufacturing: A critical starting material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	2-Oxo-4-Trifluoromethyl-2,5,6,7-Tetrahydro-1H-[1]Pyridindine-3-Carbonitrile
CAS No.	371967-27-0
Molecular Formula	C8H6F3N3O
Molecular Weight	217.15 g/mol
Synonyms	4-(Trifluoromethyl)-2-oxo-1,2,5,6,7,8-hexahydro-3-quinolinecarbonitrile; 2-Oxo-4-(trifluoromethyl)-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrile; 1,4,5,6,7,8-Hexahydro-4-(trifluoromethyl)-2-oxo-3-quinolinecarbonitrile; 4-Trifluoromethyl-2-oxo-1,2,5,6,7,8-hexahydroquinoline-3-carbonitrile; 3-Cyano-4-(trifluoromethyl)-5,6,7,8-tetrahydro-1H-quinolin-2-one; 371967-27-0; 4-Trifluoromethyl-2-oxo-1,2,5,6,7,8-hexahydro-3-quinolinecarbonitrile
EINECS	Contact for details

Quality Control

Every batch of 2-Oxo-4-Trifluoromethyl-2,5,6,7-Tetrahydro-1H-[1]Pyridindine-3-Carbonitrile is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for demanding R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.