Description

Ethyl-5(3-Fluorophenyl)-Isoxazole-3-Carboxylate is a high-purity fluorinated isoxazole derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile scaffold for constructing complex molecules with tailored biological and material properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorinated isoxazole moiety.
• Material Science: Acts as a monomer or functional additive in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probe: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and as a molecular probe to investigate biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	Ethyl-5(3-Fluorophenyl)-Isoxazole-3-Carboxylate
CAS No.	371157-14-1
Molecular Formula	C12H10FNO3
Molecular Weight	235.21 g/mol
Synonyms	Ethyl 5-(3-fluorophenyl)isoxazole-3-carboxylate; 3-Isoxazolecarboxylic acid, 5-(3-fluorophenyl)-, ethyl ester; 5-(3-Fluorophenyl)-3-isoxazolecarboxylic acid ethyl ester; 371157-14-1; Ethyl 5-(m-fluorophenyl)isoxazole-3-carboxylate; 3-Carbethoxy-5-(3-fluorophenyl)isoxazole
EINECS	Contact for details

Quality Control

Our Ethyl-5(3-Fluorophenyl)-Isoxazole-3-Carboxylate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong alkalis and incompatible organic solvents. The container must be kept tightly closed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.