Description

4-(2-Fluorophenyl)-2-Methyl-5-Oxo-4,5-Dihydro-1H-Indeno[1,2-B]Pyridine-3-Carbonitrile is a high-purity, advanced pharmaceutical intermediate with a complex fused-ring structure. This compound matters as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for research into therapeutic agents targeting central nervous system and inflammatory pathways. It is primarily needed by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and fine chemical producers engaged in developing next-generation small-molecule drugs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of novel drug candidates, especially in medicinal chemistry programs.
• Research & Development: Used in academic and industrial R&D for structure-activity relationship (SAR) studies and the discovery of new biologically active molecules.
• API Synthesis: A crucial scaffold for constructing complex molecules intended for preclinical and clinical development stages.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development, validation, and quality control in pharmaceutical analysis.
• Organic Synthesis Building Block: Utilized in specialized organic reactions to create libraries of compounds for high-throughput screening.

Basic Information

Product Name	4-(2-Fluorophenyl)-2-Methyl-5-Oxo-4,5-Dihydro-1H-Indeno[1,2-B]Pyridine-3-Carbonitrile
CAS No.	371137-43-8
Molecular Formula	C20H13FN2O
Molecular Weight	316.33 g/mol
Synonyms	4-(2-Fluorophenyl)-2-methyl-5-oxo-4,5-dihydro-1H-indeno[1,2-b]pyridine-3-carbonitrile; 1H-Indeno[1,2-b]pyridine-3-carbonitrile, 4,5-dihydro-4-(2-fluorophenyl)-2-methyl-5-oxo-; 371137-43-8; 4-(2-Fluorophenyl)-2-methyl-1,5-dihydro-5-oxoindeno[1,2-b]pyridine-3-carbonitrile; Indeno[1,2-b]pyridine-3-carbonitrile derivative; 4-(o-Fluorophenyl)-2-methyl-5-oxo-4,5-dihydro-1H-indeno[1,2-b]pyridine-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 4-(2-Fluorophenyl)-2-Methyl-5-Oxo-4,5-Dihydro-1H-Indeno[1,2-B]Pyridine-3-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.