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3-(((3,4-Difluorophenyl)Amino)Methylene)-1,5-Dioxaspiro[5.5]Undecane-2,4-Dione CAS NO 369398-61-8


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CAS No.:369398-61-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-(((3,4-Difluorophenyl)Amino)Methylene)-1,5-Dioxaspiro[5.5]Undecane-2,4-Dione is a sophisticated spirocyclic dione derivative, serving as a critical advanced intermediate in modern organic synthesis. Its unique molecular architecture, featuring a difluorophenylamino moiety, makes it a valuable building block for constructing complex molecules with tailored properties. This high-purity compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients.

Application

  • Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or requiring fluorinated bioactive molecules.
  • Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides where the difluorophenyl group can enhance biological activity and environmental stability.
  • Material Science: Potential monomer or cross-linking agent for creating specialized polymers with unique thermal or optical properties.
  • Chemical Synthesis: Versatile scaffold for constructing complex heterocycles and spirocyclic compounds in academic and industrial research laboratories.
  • Fluorine Chemistry: A valuable reagent for introducing fluorinated aromatic systems into target molecules, a common strategy in modern medicinal chemistry.

Basic Information

Product Name 3-(((3,4-Difluorophenyl)Amino)Methylene)-1,5-Dioxaspiro[5.5]Undecane-2,4-Dione
CAS No. 369398-61-8
Molecular Formula C₁₈H₁₉F₂NO₄
Molecular Weight 351.35 g/mol
Synonyms 1,5-Dioxaspiro[5.5]undecane-2,4-dione, 3-(((3,4-difluorophenyl)amino)methylene)-; 3-((3,4-Difluorophenylimino)methyl)-1,5-dioxaspiro[5.5]undecane-2,4-dione; (3,4-Difluorophenylamino)methylene Meldrum's acid derivative; Spiro Meldrum's acid difluoroaniline derivative; CAS 369398-61-8
EINECS Contact for details

Quality Control

Our 3-(((3,4-Difluorophenyl)Amino)Methylene)-1,5-Dioxaspiro[5.5]Undecane-2,4-Dione is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures material integrity for your most sensitive R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Melting Point Contact for details
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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