Description

6-Oxaspiro[4.5]Dec-2-Ene-8,9,10-Triol, 7-(Hydroxymethyl)-, (7R,8S,9S,10R)- (9Ci) is a high-purity, stereochemically defined spirocyclic compound that serves as a critical chiral building block and advanced intermediate in complex organic synthesis. Its unique polyhydroxylated spirocyclic structure makes it a valuable scaffold for pharmaceutical research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) and complex natural product analogs. This compound is primarily targeted at research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and fine chemical sectors, where precise stereochemistry and high purity are paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, including antiviral, anticancer, and anti-inflammatory drugs.
• Agrochemical Synthesis: Used as a building block for creating advanced, stereospecific pesticides and herbicides with enhanced efficacy and selectivity.
• Fine Chemical Production: Serves as a precursor in the synthesis of complex flavors, fragrances, and specialty chemicals requiring specific stereochemistry.
• Academic & Industrial Research: A valuable tool for methodological development in organic synthesis, asymmetric catalysis, and medicinal chemistry studies.
• Bioconjugate Chemistry: The multiple hydroxyl groups provide handles for conjugation, useful in developing drug delivery systems or diagnostic probes.
• Natural Product Analog Synthesis: Employed in the semi-synthesis or total synthesis of complex natural products with similar spirocyclic or polyol motifs.

Basic Information

Product Name	6-Oxaspiro[4.5]Dec-2-Ene-8,9,10-Triol, 7-(Hydroxymethyl)-, (7R,8S,9S,10R)- (9Ci)
CAS No.	369397-29-5
Molecular Formula	C10H16O5
Molecular Weight	216.23 g/mol
Synonyms	(7R,8S,9S,10R)-7-(Hydroxymethyl)-6-oxaspiro[4.5]dec-2-ene-8,9,10-triol; 7-(Hydroxymethyl)-6-oxaspiro[4.5]dec-2-ene-8,9,10-triol, (7R,8S,9S,10R)-; 6-Oxaspiro[4.5]dec-2-ene-8,9,10-triol, 7-(hydroxymethyl)-, (7R,8S,9S,10R)-; CAS 369397-29-5; (7R,8S,9S,10R)-7-(Hydroxymethyl)-6-oxaspiro[4.5]dec-2-ene-8,9,10-triol (9CI); A spirocyclic polyol derivative.
EINECS	Contact for details

Quality Control

Our 6-Oxaspiro[4.5]Dec-2-Ene-8,9,10-Triol, 7-(Hydroxymethyl)-, (7R,8S,9S,10R)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure high chemical and stereochemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended long-term storage at 2-8°C. Allow the sealed container to reach ambient temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.