Description

6-Fluoro-Imidazo[1,2-A]Pyridine-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is of significant commercial importance for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the synthesis of innovative drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, especially those targeting the central nervous system (CNS) and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides due to its bioactive heterocyclic core.
• Material Science: Serves as a precursor for the synthesis of specialized ligands and functional organic materials.
• Academic & Industrial R&D: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.
• Contract Manufacturing: Supplied to CDMOs for scale-up and custom synthesis projects under cGMP conditions.

Basic Information

Product Name	6-Fluoro-Imidazo[1,2-A]Pyridine-2-Carboxylic Acid
CAS No.	367900-94-5
Molecular Formula	C8H5FN2O2
Molecular Weight	180.14 g/mol
Synonyms	6-Fluoroimidazo[1,2-a]pyridine-2-carboxylic acid; 2-Carboxy-6-fluoroimidazo[1,2-a]pyridine; 6-Fluoro-1H-imidazo[1,2-a]pyridine-2-carboxylic acid; 367900-94-5; 6-Fluoroimidazo[1,2-a]pyridine-2-carboxylate; Imidazo[1,2-a]pyridine-2-carboxylic acid, 6-fluoro-; 6-F-Imidazo[1,2-a]Py-2-COOH
EINECS	Contact for details

Quality Control

Our 6-Fluoro-Imidazo[1,2-A]Pyridine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to ISO 9001 standards, and material can be supplied to meet the requirements of cGMP and ICH Q7 guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.