Description

tert-Butyl 2-Amino-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a complex fused heterocyclic structure. This compound is critically important for its role as a key building block in the synthesis of novel, biologically active molecules, particularly in medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of new therapeutic agents, where precise chemical architecture and reliable quality are paramount.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) and develop new chemical entities.
• API Synthesis: Acts as a key scaffold in the construction of complex active pharmaceutical ingredients (APIs) for preclinical and clinical studies.
• Chemical Biology Probes: Employed in the development of specialized molecular probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds under cGMP conditions.
• Academic Research: Utilized in university and institutional laboratories for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	tert-Butyl 2-Amino-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate
CAS No.	365996-05-0
Molecular Formula	C11H17N3O2S
Molecular Weight	255.34 g/mol
Synonyms	5-(tert-Butoxycarbonyl)-2-amino-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine; 2-Amino-5-(tert-butoxycarbonyl)-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine; tert-Butyl 2-amino-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-5-carboxylate; 2-Amino-6,7-dihydro-4H-thiazolo[5,4-c]pyridine-5-carboxylic acid tert-butyl ester; BOC-protected 2-aminothiazolopyridine; CAS 365996-05-0
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Amino-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques including HPLC, NMR, and MS. We are committed to meeting the stringent requirements of our global pharmaceutical and fine chemical partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and desiccated upon opening to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.