Description

tert-Butyl 3-isocyanopropionate is a versatile and reactive chemical building block used in advanced organic synthesis. Its value lies in the combination of a protected carboxylic acid group and a highly reactive isocyanate functionality, enabling efficient multi-step transformations. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for constructing complex molecules and active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring peptide-like or urea-based linkages.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where its reactive groups facilitate the creation of novel heterocyclic structures.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for specialty polymers, such as polyurethanes and polyamides, with tailored properties.
• Peptidomimetics & Bioconjugation: Enables the synthesis of peptidomimetic compounds and is used as a linker for bioconjugation in drug delivery and diagnostic applications.
• Organic Synthesis Reagent: A valuable reagent for introducing the tert-butyl propionate moiety and isocyanate group in multi-component reactions and heterocycle formation.
• Material Science Research: Employed in developing novel functional materials, coatings, and adhesives with specific chemical resistance or bonding characteristics.

Basic Information

Product Name	tert-Butyl 3-Isocyanopropionate
CAS No.	364046-20-8
Molecular Formula	C8H13NO3
Molecular Weight	171.19 g/mol
Synonyms	3-Isocyanopropionic Acid tert-Butyl Ester; tert-Butyl β-Isocyanopropionate; Propanoic Acid, 3-Isocyanato-, 1,1-Dimethylethyl Ester; 1,1-Dimethylethyl 3-Isocyanatopropanoate; 3-Isocyanato-1-tert-butoxy-1-oxopropane; tert-Butyl 3-Isocyanatopropanoate; NSC 405124; tert-Butoxycarbonylethyl Isocyanate
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-isocyanopropionate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.