Description

4-Isoxazolecarboxylic Acid, 3-Ethyl-5-(Trifluoromethyl)-, Ethyl Ester is a high-value fluorinated heterocyclic building block, specifically an ethyl ester derivative of an isoxazole carboxylic acid. This compound is prized for its unique molecular architecture, combining an isoxazole core with ethyl and trifluoromethyl substituents, which imparts significant electronic and steric properties for advanced synthesis. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients. The CAS number for this compound is 363617-95-2.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for molecules targeting central nervous system (CNS) disorders, anti-infectives, and metabolic diseases.
• Agrochemical Active Ingredient Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, or organic electronic materials due to its rigid heterocyclic structure and fluorine content.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and enzyme inhibitors for biochemical and pharmacological research.
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis houses serving the life sciences sector, enabling the production of complex, patent-protected molecules.

Basic Information

Item	Detail
Product Name	4-Isoxazolecarboxylic Acid, 3-Ethyl-5-(Trifluoromethyl)-, Ethyl Ester
CAS No.	363617-95-2
Molecular Formula	C9H10F3NO3
Molecular Weight	237.18 g/mol
Synonyms	Ethyl 3-ethyl-5-(trifluoromethyl)isoxazole-4-carboxylate; 3-Ethyl-5-(trifluoromethyl)-4-isoxazolecarboxylic acid ethyl ester; 4-Isoxazolecarboxylic acid, 3-ethyl-5-(trifluoromethyl)-, ethyl ester; 363617-95-2; Ethyl 3-ethyl-5-trifluoromethylisoxazole-4-carboxylate; AI3-36361795-2
EINECS	Contact for details

Quality Control

Our production of 4-Isoxazolecarboxylic Acid, 3-Ethyl-5-(Trifluoromethyl)-, Ethyl Ester adheres to stringent in-process controls and final release testing protocols. We guarantee batch-to-batch consistency and high purity to meet the exacting standards of advanced organic synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to ensure full traceability and compliance with your internal quality systems.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.