Description

2,5-Dioxopyrrolidin-1-Yl 6-(2-(Propan-2-Ylidene)Hydrazinyl)Nicotinate (S-Sanh) is a specialized heterocyclic compound that serves as a high-value synthetic intermediate and building block. This product is critical for enabling precise chemical modifications in advanced research and development, particularly in the synthesis of complex molecules. It is primarily sought after by pharmaceutical R&D laboratories, agrochemical innovators, and fine chemical manufacturers for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly for targeted therapies.
• Bioconjugation Reagent: Used in the development of antibody-drug conjugates (ADCs) and other biopharmaceuticals due to its reactive ester moiety.
• Agrochemical Research: Intermediate for creating new-generation pesticides and herbicides with specific modes of action.
• Material Science: Precursor for functional polymers and advanced organic electronic materials.
• Chemical Biology Probes: Enables the labeling and study of biological processes and protein interactions.
• Peptide Synthesis: Acts as an activating agent for carboxylic acids in solid-phase and solution-phase peptide coupling.

Basic Information

Product Name	2,5-Dioxopyrrolidin-1-Yl 6-(2-(Propan-2-Ylidene)Hydrazinyl)Nicotinate (S-Sanh)
CAS No.	362522-50-7
Molecular Formula	C13H12N4O4
Molecular Weight	288.26 g/mol
Synonyms	6-Hydrazinyl-2-(propan-2-ylidene)nicotinic acid 2,5-dioxopyrrolidin-1-yl ester; S-Sanh; 6-(2-Isopropylidenehydrazinyl)nicotinic acid N-hydroxysuccinimide ester; N-Succinimidyl 6-(2-isopropylidenehydrazinyl)nicotinate; 362522-50-7; Nicotinic acid, 6-(2-(1-methylethylidene)hydrazinyl)-, 2,5-dioxo-1-pyrrolidinyl ester; 1-[(2,5-Dioxopyrrolidin-1-yl)oxy]-6-[(2-propan-2-ylidenehydrazinyl)]-1-oxidanylidene-pyridine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2,5-Dioxopyrrolidin-1-Yl 6-(2-(Propan-2-Ylidene)Hydrazinyl)Nicotinate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and cGMP-grade synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.