Description

4-Azido-1H-Pyrrolo[2,3-B]Pyridine is a specialized heterocyclic building block featuring a reactive azido functional group. This compound is of significant value in medicinal chemistry and materials science for its utility in click chemistry reactions, particularly the copper-catalyzed azide-alkyne cycloaddition (CuAAC). It is primarily sought after by research institutions and pharmaceutical companies engaged in the synthesis of novel drug candidates, bioconjugates, and functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex molecules in drug discovery programs, particularly for kinase inhibitors and other targeted therapies.
• Bioconjugation & Probe Development: Used to label biomolecules (proteins, nucleic acids) for imaging, diagnostics, and studying biological pathways via click chemistry.
• Polymer & Materials Science: Serves as a functional monomer or cross-linker for creating smart polymers, hydrogels, and surface-modified materials with specific properties.
• Agrochemical Research: Employed in the synthesis of novel active ingredients for crop protection products.
• Chemical Biology Tool: Facilitates activity-based protein profiling (ABPP) and the development of chemical probes to interrogate enzyme function.

Basic Information

Product Name	4-Azido-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	361370-27-6
Molecular Formula	C7H5N5
Molecular Weight	159.15 g/mol
Synonyms	4-Azido-7-azaindole; 4-Azido-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 4-azido-; 4-Azido-7-aza-indole; 4-Azido-1H-7-azaindole; 4-N3-7-Azaindole; 4-Azido-1H-pyrrolo[2,3-b]pyridine (7-azaindole derivative)
EINECS	Contact for details

Quality Control

Our 4-Azido-1H-Pyrrolo[2,3-B]Pyridine is manufactured under strict quality protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Area %)
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.