Description

Azido-Peg7-Acid is a heterobifunctional polyethylene glycol (PEG) derivative featuring a reactive azide group at one terminus and a carboxylic acid group at the other. This bifunctionality is critical for creating stable, biocompatible linkages in advanced bioconjugation and materials science applications. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostics industries for developing targeted drug delivery systems, modifying biomolecules, and synthesizing functional hydrogels.

Application

• Bioconjugation Linker: Used to covalently attach drug molecules, peptides, or fluorescent dyes to antibodies, proteins, or nanoparticles via click chemistry (azide-alkyne cycloaddition) and amide bond formation.
• PEGylation Reagent: Serves as a spacer to PEGylate therapeutic proteins or peptides, enhancing their solubility, stability, and circulation half-life while reducing immunogenicity.
• Crosslinking Agent: Employed in the synthesis of hydrogels and polymer networks for tissue engineering scaffolds and controlled-release drug delivery matrices.
• Surface Functionalization: Modifies the surface of materials (e.g., gold nanoparticles, silicon chips, magnetic beads) to introduce bio-recognition elements for biosensor and diagnostic assay development.
• ADC (Antibody-Drug Conjugate) Development: Acts as a key building block for constructing cleavable or non-cleavable linkers in ADC payload attachment strategies.
• Probe Synthesis: Facilitates the creation of activity-based probes and imaging agents for studying biological processes in vitro and in vivo.

Basic Information

Product Name	Azido-Peg7-Acid
CAS No.	361189-66-4
Molecular Formula	C17H33N3O9
Molecular Weight	447.46 g/mol
Synonyms	Azido-PEG7-acid; 2-[2-[2-[2-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetic acid; 17-Aza-3,6,9,12,15-pentaoxahenicos-16-ynoic acid, 20-azido-; Azido-EG7-acid; N3-PEG7-COOH; Azidoheptaethylene glycol carboxylic acid; Azido-PEG7-COOH; α-Azido-ω-carboxy heptaethylene glycol
EINECS	Contact for details

Quality Control

Our Azido-Peg7-Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FT-IR, to ensure high purity and consistent performance for sensitive research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below under desiccant. This compound is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or oil
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.