Description

4-Fluoro-2,3,4,5-Tetrahydro-1H-2-Benzazepine Hydrochloride is a high-purity, fluorinated benzazepine derivative, a key structural motif in medicinal chemistry. This compound serves as a versatile and critical building block for pharmaceutical research and development, enabling the synthesis of novel drug candidates. It is primarily utilized by pharmaceutical companies, contract research organizations (CROs), and academic research laboratories focused on central nervous system (CNS) and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential therapeutic agents targeting neurological disorders.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Reference Standard: Serves as a high-purity analytical standard for method development and quality control in API manufacturing.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening (HTS) campaigns.
• Process Chemistry Development: Used in scaling up synthetic routes for advanced pharmaceutical intermediates.
• Academic Research: A valuable reagent for investigating the pharmacology and biochemistry of benzazepine-based compounds.

Basic Information

Product Name	4-Fluoro-2,3,4,5-Tetrahydro-1H-2-Benzazepine Hydrochloride
CAS No.	360054-82-6
Molecular Formula	C10H13FN•HCl
Molecular Weight	201.68 g/mol (Free base: 165.22 g/mol)
Synonyms	4-Fluoro-2,3,4,5-tetrahydro-1H-2-benzazepine hydrochloride; 1H-2-Benzazepine, 4-fluoro-2,3,4,5-tetrahydro-, hydrochloride; 4-Fluoro-1,2,3,5-tetrahydro-2-benzazepine HCl; 4-Fluorotetrahydro-2-benzazepine hydrochloride; 2-Benzazepine, 4-fluoro-2,3,4,5-tetrahydro-, hydrochloride; 360054-82-6 (CAS); 4-Fluoro-2,3,4,5-tetrahydro-1H-2-benzazepine HCl
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2,3,4,5-Tetrahydro-1H-2-Benzazepine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with the standards expected for pharmaceutical-grade intermediates in research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.