Description

Spiro[1-Azabicyclo[3.2.1]Octane-6,5-Oxazolidin]-2-One, (5R)- (9Ci) is a complex, chiral spirocyclic organic compound featuring a fused bicyclic and oxazolidinone structure. This compound matters as a sophisticated pharmaceutical intermediate or research chemical used in the synthesis of novel active molecules, where its defined stereochemistry is critical for biological activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for drug discovery programs targeting neurological and other therapeutic areas.

Application

• Key Intermediate in Pharmaceutical Synthesis: Serves as a critical building block for the development of new drug candidates, particularly those with complex polycyclic architectures.
• Neurological Research: Used in the research and synthesis of compounds targeting central nervous system (CNS) receptors and enzymes, leveraging its constrained, nitrogen-containing bicyclic scaffold.
• Chiral Pool Synthesis: Provides a source of defined (5R) stereochemistry for asymmetric synthesis, enabling the construction of enantiomerically pure final products.
• Medicinal Chemistry Exploration: Acts as a versatile scaffold for generating focused libraries to study structure-activity relationships (SAR) in early-stage drug discovery.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization studies for the commercial-scale production of advanced pharmaceutical intermediates (APIs).
• Academic & Institutional Research: Utilized in universities and research institutes for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	Spiro[1-Azabicyclo[3.2.1]Octane-6,5-Oxazolidin]-2-One, (5R)- (9Ci)
CAS No.	360044-53-7
Molecular Formula	C9H14N2O2
Molecular Weight	182.22 g/mol
Synonyms	(5R)-Spiro[1-azabicyclo[3.2.1]octane-6,5'-oxazolidin]-2'-one; (5R)-Spiro[1-azabicyclo[3.2.1]octane-6,5-oxazolidin]-2-one; 360044-53-7; (5R)-Spiro[1-Azabicyclo[3.2.1]octane-6,5'-oxazolidin]-2'-one; Spiro[1-azabicyclo[3.2.1]octane-6,5'-oxazolidin]-2'-one, (5R)-; (R)-Spiro[1-azabicyclo[3.2.1]octane-6,5'-oxazolidin]-2'-one
EINECS	Contact for details

Quality Control

Our Spiro[1-Azabicyclo[3.2.1]Octane-6,5-Oxazolidin]-2-One, (5R)- (9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). For long-term storage, consider keeping the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.