Description

(1S,2S)-trans-1-Hydroxy-1,2-Dihydro-2-Naphthyl Benzoate is a high-purity, stereochemically defined organic compound that serves as a critical chiral building block and intermediate in advanced chemical synthesis. Its precise stereochemistry and functional groups make it a valuable scaffold for developing pharmaceuticals, agrochemicals, and specialty materials. This compound is essential for research and development chemists and process engineers in the pharmaceutical, fine chemical, and advanced material sectors who require high-fidelity chiral intermediates.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting specific stereoisomer requirements.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where stereoselectivity impacts biological activity.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and flavors & fragrances.
• Material Science Research: Potential monomer or modifier in the development of polymers with specific optical or structural properties.
• Academic & Industrial R&D: A valuable reference standard and reagent for methodological development in organic and medicinal chemistry laboratories.

Basic Information

Product Name	(1S,2S)-trans-1-Hydroxy-1,2-Dihydro-2-Naphthyl Benzoate
CAS No.	359820-45-4
Molecular Formula	C₁₇H₁₄O₃
Molecular Weight	266.29 g/mol
Synonyms	(1S,2S)-1-Hydroxy-1,2-dihydronaphthalen-2-yl benzoate; trans-(1S,2S)-1,2-Dihydro-1-hydroxy-2-naphthyl benzoate; (1S,2S)-1,2-Dihydro-1-hydroxy-2-naphthalenyl benzoate; Benzoic acid (1S,2S)-1,2-dihydro-1-hydroxy-2-naphthyl ester; (1S,2S)-HDB; (1S,2S)-trans-HDNB; Chiral dihydronaphthyl benzoate; Stereoisomer of 1-hydroxy-1,2-dihydro-2-naphthyl benzoate
EINECS	Contact for details

Quality Control

Our (1S,2S)-trans-1-Hydroxy-1,2-Dihydro-2-Naphthyl Benzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets exacting specifications for research and process chemistry. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee identity, purity, and stereochemical integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (1S,2S isomer)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.