Description

n-Boc-2-Amino-4-Azido-Butanoic Acid Methyl Ester is a protected amino acid derivative that serves as a versatile and critical building block in advanced organic synthesis. Its value lies in the orthogonal protection of the amine group by the Boc group and the presence of a reactive azido functionality, enabling selective transformations and peptide modifications. This compound is essential for researchers and manufacturers in pharmaceutical development, peptide chemistry, and bioconjugation, particularly for creating novel drug candidates and labeled biomolecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex active pharmaceutical ingredients (APIs) and peptide-based therapeutics.
• Peptide Synthesis & Modification: Used in solid-phase and solution-phase peptide synthesis to introduce azido handles for subsequent "click chemistry" reactions like CuAAC.
• Bioconjugation & Probe Development: Facilitates the site-specific labeling of proteins, antibodies, and other biomolecules with fluorescent dyes, polymers, or drugs via azide-alkyne cycloaddition.
• Chemical Biology Research: Enables the study of protein function and interactions through the incorporation of bioorthogonal tags into cellular systems.
• Material Science: Serves as a monomer or cross-linker for creating functionalized polymers and smart materials with tailored properties.
• Library Synthesis for Drug Discovery: Used in combinatorial chemistry to generate diverse compound libraries for high-throughput screening.

Basic Information

Product Name	n-Boc-2-Amino-4-Azido-Butanoic Acid Methyl Ester
CAS No.	359781-97-8
Molecular Formula	C10H18N4O4
Molecular Weight	258.28 g/mol
Synonyms	Boc-Aad(3-N3)-OMe; (2S)-2-[(tert-Butoxycarbonyl)amino]-4-azidobutanoic acid methyl ester; Methyl (2S)-2-{[(tert-butoxy)carbonyl]amino}-4-azidobutanoate; Boc-L-2,4-diaminobutanoic acid 4-azido methyl ester; 4-Azido-L-2,4-diaminobutanoic acid N-Boc methyl ester; Azido-PEG2-Boc-OSu precursor; Boc-protected azido amino acid ester
EINECS	Contact for details

Quality Control

Our n-Boc-2-Amino-4-Azido-Butanoic Acid Methyl Ester is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and cGMP applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with ISO, REACH, and other relevant regulatory frameworks to meet the stringent requirements of the global pharmaceutical supply chain.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. The compound is light-sensitive (store away from light). Allow the container to reach room temperature before opening to minimize moisture condensation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.