Description

2-(2-Trimethylsilanyloxy-Ethoxy)-Ethylamine is a specialized organosilicon compound featuring a protected amine group linked via a flexible ethoxy spacer to a trimethylsilyl (TMS) ether. This unique structure makes it a valuable synthetic intermediate and protecting group reagent in advanced organic synthesis. It is primarily utilized by pharmaceutical, agrochemical, and advanced materials researchers for the controlled introduction and subsequent deprotection of amine functionalities in complex molecule construction.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly where temporary amine protection is required.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require specific amine-containing scaffolds.
• Polymer & Material Science: Serves as a functional monomer or cross-linking agent for creating specialty silicones, coatings, and adhesives with tailored properties.
• Peptide Chemistry: Acts as a protecting group reagent for amino acids during solid-phase peptide synthesis (SPPS).
• Surface Modification: Employed to functionalize silica, glass, or other oxide surfaces with amine groups for further chemical attachment.
• Ligand & Catalyst Development: Used in the preparation of novel ligands for metal complexes and organocatalysts.

Basic Information

Product Name	2-(2-Trimethylsilanyloxy-Ethoxy)-Ethylamine
CAS No.	359630-83-4
Molecular Formula	C9H23NO2Si
Molecular Weight	205.37 g/mol
Synonyms	2-[2-(Trimethylsilyloxy)ethoxy]ethanamine; 2-(2-(Trimethylsilyloxy)ethoxy)ethylamine; N-[2-[2-(Trimethylsilyl)oxy]ethoxy]ethyl]amine; Amino-PEG2-TMS; TMS-PEG2-Amine; 2-(2-(Trimethylsiloxy)ethoxy)ethylamine; (2-(2-Aminoethoxy)ethoxy)trimethylsilane
EINECS	Contact for details

Quality Control

Our production of 2-(2-Trimethylsilanyloxy-Ethoxy)-Ethylamine adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. All materials are characterized using advanced analytical techniques including GC, HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We support cGMP and ISO 9001 compliant manufacturing practices for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.