Description

Methyl 3-(tert-Butyldimethylsilyloxy)-2-Methylbenzoate is a high-purity, protected benzoate derivative that serves as a critical synthetic intermediate in advanced organic synthesis. Its value lies in the tert-butyldimethylsilyl (TBDMS) protecting group, which provides exceptional stability for sensitive functional group manipulations. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing complex active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in constructing complex aromatic and heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where specific benzoate motifs are required.
• Material Science Research: Serves as a monomer or precursor in the development of specialty polymers and advanced organic materials.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in synthetic organic chemistry, especially in protecting group strategies.
• Fine Chemical Production: Intermediate in the multi-step synthesis of flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	Methyl 3-(tert-Butyldimethylsilyloxy)-2-Methylbenzoate
CAS No.	359629-73-5
Molecular Formula	C15H24O3Si
Molecular Weight	280.44 g/mol
Synonyms	Methyl 2-Methyl-3-[(tert-butyldimethylsilyl)oxy]benzoate; 3-[(tert-Butyldimethylsilyl)oxy]-2-methylbenzoic Acid Methyl Ester; 2-Methyl-3-(TBDMSO)benzoic Acid Methyl Ester; Methyl 3-(TBDMS-oxy)-2-methylbenzoate; Benzoic acid, 3-[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-methyl-, methyl ester; TBDMS-protected Methyl 2-Methyl-3-hydroxybenzoate
EINECS	Contact for details

Quality Control

Our Methyl 3-(tert-Butyldimethylsilyloxy)-2-Methylbenzoate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques (HPLC, GC, NMR). We support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can compromise product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.