Description

(1R,2R)-Ethyl 2-((S)-1-Phenylethylamino)Cyclopentanecarboxylate CAS NO 359586-67-7 is a high-purity chiral intermediate of significant importance in asymmetric synthesis. This compound matters because it provides a critical, stereochemically defined building block for the construction of complex pharmaceutical molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of novel drug candidates, especially those targeting neurological pathways.
• Asymmetric Catalysis Research: Used as a ligand precursor or a model substrate in the development and study of new stereoselective catalytic reactions.
• API Development: Serves as a critical intermediate in the production route for advanced Active Pharmaceutical Ingredients (APIs) requiring high enantiomeric purity.
• Chemical Biology Probes: Employed in the synthesis of specialized molecular probes for studying enzyme mechanisms and receptor interactions.
• Process Chemistry Optimization: Utilized by process chemists to scale up and optimize synthetic routes from laboratory to pilot plant scale.
• Academic & Industrial R&D: A valuable compound for research in synthetic organic chemistry within both academic settings and industrial R&D departments.

Basic Information

Product Name	(1R,2R)-Ethyl 2-((S)-1-Phenylethylamino)Cyclopentanecarboxylate
CAS No.	359586-67-7
Molecular Formula	C16H23NO2
Molecular Weight	261.36 g/mol
Synonyms	Ethyl (1R,2R)-2-[(1S)-1-phenylethylamino]cyclopentanecarboxylate; (1R,2R)-Ethyl 2-((S)-1-Phenylethylamino)Cyclohexanecarboxylate (common error); (1R,2R)-Ethyl 2-[(1S)-1-phenylethylamino]cyclopentanecarboxylate; (1R,2R)-Ethyl 2-((S)-α-methylbenzylamino)cyclopentanecarboxylate; (1R,2R)-Ethyl 2-[(S)-1-phenylethylamino]cyclopentane-1-carboxylate; (1R,2R)-Ethyl 2-((S)-1-phenylethylamino)cyclopentane carboxylate; (1R,2R)-Ethyl 2-[(S)-1-phenylethylamino]cyclopentanecarboxylic acid ethyl ester; (1R,2R)-Ethyl 2-((S)-1-phenylethylamino)cyclopentane-1-carboxylate
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Quality Control

Our (1R,2R)-Ethyl 2-((S)-1-Phenylethylamino)Cyclopentanecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure compliance with high-purity pharmaceutical intermediate standards, with a focus on chiral purity and chemical identity. Comprehensive Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.