Description

Methyl3,4-o-Isopropylidene-D-Lyxonate CAS NO 359437-02-8 is a high-purity, protected carbohydrate derivative, specifically a methyl ester of an isopropylidene-protected lyxonic acid. This compound is a critical chiral building block and synthetic intermediate in advanced organic synthesis, valued for its defined stereochemistry and functional group compatibility. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of nucleoside analogs, antiviral agents, and complex bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel nucleoside and nucleotide analogs for antiviral and anticancer research.
• Organic Synthesis Building Block: Used in the construction of complex natural products and sugar-modified compounds due to its protected diol functionality.
• Carbohydrate Chemistry: Essential for preparing selectively protected sugar derivatives for glycosylation studies and oligosaccharide synthesis.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to develop new therapeutic agents targeting viral polymerases.
• Process Chemistry Development: Used in scaling up routes to active pharmaceutical ingredients (APIs) that require a defined sugar backbone.
• Bioconjugation & Probe Development: Acts as a starting material for synthesizing labeled sugars or carbohydrate-based probes for biochemical assays.

Basic Information

Product Name	Methyl3,4-o-Isopropylidene-D-Lyxonate
CAS No.	359437-02-8
Molecular Formula	C9H16O6
Molecular Weight	220.22 g/mol
Synonyms	Methyl 3,4-O-Isopropylidene-D-lyxonate; D-Lyxonic acid, 3,4-O-(1-methylethylidene)-, methyl ester; Methyl (3,4-O-isopropylidene-D-lyxonate); Methyl 3,4-O-(1-methylethylidene)-D-lyxonate; Isopropylidene-D-lyxonic acid methyl ester; 359437-02-8; D-Lyxonate derivative, methyl isopropylidene acetal
EINECS	Contact for details

Quality Control

Our Methyl3,4-o-Isopropylidene-D-Lyxonate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and spectroscopic identification (NMR, IR), to ensure it meets the high standards required for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformance to specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation by atmospheric moisture. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity	≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.