Description

Methyl 2-Iodo-5-Hydroxybenzoate is a high-purity, halogenated aromatic ester building block of significant interest in advanced organic synthesis. Its unique structure, featuring both an iodine substituent and a phenolic hydroxyl group, makes it a versatile intermediate for constructing complex molecules. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibitors and receptor modulators.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators, leveraging its halogenated aromatic core.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Precursor: Employed in the research and development of organic electronic materials, liquid crystals, and advanced polymers.
• Chemical Biology Probes: Useful for synthesizing tagged molecules and probes for studying biological pathways and protein interactions.
• Custom Synthesis and Scale-Up: Available for contract research organizations (CROs) and CDMOs requiring a reliable, high-quality intermediate for custom synthesis projects from gram to kilogram scale.

Basic Information

Product Name	Methyl 2-Iodo-5-Hydroxybenzoate
CAS No.	358672-64-7
Molecular Formula	C8H7IO3
Molecular Weight	278.05 g/mol
Synonyms	2-Iodo-5-hydroxybenzoic acid methyl ester; Methyl 5-hydroxy-2-iodobenzoate; Benzoic acid, 2-iodo-5-hydroxy-, methyl ester; 5-Hydroxy-2-iodobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of Methyl 2-Iodo-5-Hydroxybenzoate is produced and tested under a strict quality management system. We ensure compliance with high-purity standards suitable for research and development applications. Comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, is performed to verify identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.