Description

2-[6-o-Acetyl-2,3,4-Tris-o-(Phenylmethyl)-α-D-Mannopyranosyl]-n-Carbobenzoxy-L-Tryptophan Methyl Ester is a sophisticated, high-purity protected carbohydrate-amino acid conjugate, serving as a critical advanced intermediate in complex organic synthesis. This compound is engineered to provide exceptional selectivity and yield in the construction of glycopeptides and other biologically active molecules. It is an essential building block for pharmaceutical R&D, particularly for researchers and manufacturers developing novel therapeutics, diagnostic agents, and biochemical tools.

Application

• Pharmaceutical Intermediate: A key protected precursor in the multi-step synthesis of complex glycopeptides and glycoproteins with therapeutic potential.
• Glycobiology Research: Used in academic and industrial laboratories to study carbohydrate-protein interactions and enzymatic glycosylation pathways.
• Antibiotic & Antiviral Drug Development: Serves as a building block for synthesizing novel compounds targeting bacterial cell walls or viral entry mechanisms.
• Bioconjugation & Probe Synthesis: Employed in the creation of fluorescent or affinity-labeled probes for diagnostic assays and imaging studies.
• Process Chemistry & Scale-up: Provides a reliable, high-quality intermediate for optimizing and scaling synthetic routes from milligram to kilogram scale.
• Custom Synthesis & Contract Manufacturing: A critical starting material for CDMOs (Contract Development and Manufacturing Organizations) offering bespoke synthetic services.

Basic Information

Product Name	2-[6-o-Acetyl-2,3,4-Tris-o-(Phenylmethyl)-α-D-Mannopyranosyl]-n-Carbobenzoxy-L-Tryptophan Methyl Ester
CAS No.	358620-69-6
Molecular Formula	C55H56N2O12
Molecular Weight	912.04 g/mol
Synonyms	CBZ-Protected Tryptophan Mannoside Ester; N-Carbobenzoxy-L-Tryptophan α-D-Mannopyranoside Derivative; Methyl (2S)-2-[[(2S)-3-(1H-Indol-3-yl)-1-[[(phenylmethoxy)carbonyl]amino]-1-oxopropan-2-yl]amino]-2-[6-acetyloxy-2,3,4-tris(phenylmethoxy)oxan-2-yl]acetate; 358620-69-6; Protected Glycotryptophan; Mannosyl-Tryptophan Conjugate; Glycoamino Acid Building Block
EINECS	Contact for details

Quality Control

Every batch of 2-[6-o-Acetyl-2,3,4-Tris-o-(Phenylmethyl)-α-D-Mannopyranosyl]-n-Carbobenzoxy-L-Tryptophan Methyl Ester is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency, meeting the exacting standards required for pharmaceutical R&D and process development. Certificates of Analysis (COA) with detailed HPLC, NMR, and MS data are available for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. For long-term storage, consider storage under inert atmosphere (argon or nitrogen) at -20°C. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.