Description

D-Ribofuranose, 2-Deoxy-2-Fluoro-1-Acetate 3,5-Dibenzoate is a high-purity, fluorinated ribose derivative, a critical advanced pharmaceutical intermediate (API) used in the synthesis of novel nucleoside analogs. Its value lies in its precise chemical structure, which serves as a key building block for developing antiviral and anticancer therapeutics, enabling targeted modifications to drug candidates. This compound is essential for R&D and production teams in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality intermediates for complex synthetic routes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated nucleoside analogs for antiviral (e.g., hepatitis, influenza) and anticancer drug development.
• Antiviral Pro-drug Synthesis: Used in the research and manufacturing of pro-drugs designed for improved bioavailability and targeted delivery.
• Biochemical Research: Serves as a vital reagent in metabolic pathway studies and enzyme inhibition research due to its fluorinated sugar moiety.
• Radiopharmaceuticals: Potential use as a precursor for 18F-labeled compounds used in Positron Emission Tomography (PET) imaging agents.
• Glycochemistry & Glycobiology: Employed in the synthesis of modified carbohydrates and glycomimetics for studying biological recognition processes.
• Medicinal Chemistry: A versatile scaffold for structure-activity relationship (SAR) studies to optimize the potency and selectivity of new chemical entities.

Basic Information

Product Name	D-Ribofuranose, 2-Deoxy-2-Fluoro-1-Acetate 3,5-Dibenzoate
CAS No.	356783-11-4
Molecular Formula	C21H19FO7
Molecular Weight	402.37 g/mol
Synonyms	2-Deoxy-2-fluoro-1-O-acetyl-3,5-di-O-benzoyl-D-ribofuranose; 1-O-Acetyl-2-deoxy-2-fluoro-3,5-di-O-benzoyl-D-ribofuranose; 2-Fluoro-2-deoxy-1-O-acetyl-3,5-di-O-benzoyl-D-ribofuranose; 2'-Deoxy-2'-fluoro-1'-O-acetyl-3',5'-di-O-benzoyl-D-ribofuranose; 1-O-Acetyl-2-deoxy-2-fluoro-3,5-di-O-benzoyl-α/β-D-ribofuranose; Fluorinated Ribose Dibenzoate Acetate; 356783-11-4
EINECS	Contact for details

Quality Control

Our D-Ribofuranose, 2-Deoxy-2-Fluoro-1-Acetate 3,5-Dibenzoate is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity suitable for pharmaceutical applications. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity, purity, and the absence of critical impurities. Comprehensive Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.