Description

(7S)-1,4-Dioxa-8-Azaspiro[4.5]Decane-7-Carboxylic Acid is a high-purity chiral spirocyclic compound that serves as a critical advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its unique rigid spiro structure and functional groups make it invaluable for constructing complex molecular architectures with precise stereochemistry. This compound is primarily sought by pharmaceutical R&D and fine chemical synthesis teams for the development of new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Asymmetric Synthesis: Employed as a stereodefined scaffold for constructing complex molecules in medicinal chemistry and process development.
• Ligand and Catalyst Development: Used in the research and preparation of novel chiral ligands and organocatalysts for enantioselective transformations.
• Agrochemical Research: Intermediate in the development of new, high-efficacy crop protection agents with specific biological activity.
• Academic & Industrial R&D: Serves as a valuable reagent for methodological studies in organic chemistry and material science research.
• Custom Synthesis: Starting material for the contract manufacturing of bespoke fine chemicals and proprietary compounds for clients.

Basic Information

Product Name	(7S)-1,4-Dioxa-8-Azaspiro[4.5]Decane-7-Carboxylic Acid
CAS No.	356073-54-6
Molecular Formula	C9H15NO4
Molecular Weight	201.22 g/mol
Synonyms	(7S)-1,4-Dioxa-8-azaspiro[4.5]decane-7-carboxylic acid; (7S)-8-Aza-1,4-dioxaspiro[4.5]decane-7-carboxylic acid; L-Proline, 1-(2,2-dimethyl-1,3-dioxolan-4-ylmethyl)-, (S)-; (S)-1-((2,2-Dimethyl-1,3-dioxolan-4-yl)methyl)pyrrolidine-2-carboxylic acid; Spirocyclic Proline Derivative; Chiral Spirocyclic Acid; CAS 356073-54-6
EINECS	Contact for details

Quality Control

Every batch of (7S)-1,4-Dioxa-8-Azaspiro[4.5]Decane-7-Carboxylic Acid is produced and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, and NMR to ensure identity, purity, and chiral integrity. A comprehensive Certificate of Analysis (COA) detailing all specification results is provided with each shipment to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.