Description

Propanoic Acid, 2-Azido-3-Hydroxy-2-Methyl-, Methyl Ester, (2S)- (9Ci) is a specialized chiral synthon featuring an azido functional group, making it a valuable intermediate for advanced organic synthesis. Its core value lies in enabling the stereoselective construction of complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where precise stereochemistry is critical.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of chiral drug candidates, including potential protease inhibitors and other biologically active molecules.
• Agrochemical Research: Used in the development of novel, stereospecific pesticides and herbicides.
• Peptidomimetics Synthesis: Serves as a precursor for introducing azido handles into peptide analogs for click chemistry applications and bioconjugation.
• Material Science: Potential monomer or cross-linking agent for creating novel polymers with specific functional properties.
• Chemical Biology Probes: Utilized in the creation of activity-based probes and other tools for studying biological systems.
• Academic & Industrial R&D: A critical reagent for methodological development in asymmetric synthesis and organoazide chemistry.

Basic Information

Product Name	Propanoic Acid, 2-Azido-3-Hydroxy-2-Methyl-, Methyl Ester, (2S)- (9Ci)
CAS No.	356048-03-8
Molecular Formula	C6H9N3O3
Molecular Weight	171.15 g/mol
Synonyms	(2S)-2-Azido-3-hydroxy-2-methylpropanoic acid methyl ester; Methyl (2S)-2-azido-3-hydroxy-2-methylpropanoate; (S)-Methyl 2-azido-3-hydroxy-2-methylpropionate; 2-Azido-3-hydroxy-2-methylpropionic acid methyl ester, (S)-; L-2-Azido-3-hydroxy-2-methylpropionic acid methyl ester; Azidohomoserine derivative; Chiral azido alcohol ester
EINECS	Contact for details

Quality Control

Our Propanoic Acid, 2-Azido-3-Hydroxy-2-Methyl-, Methyl Ester, (2S)- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized by advanced analytical techniques including HPLC, GC, NMR, and chiral analysis. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and highly volatile. Keep away from heat, sparks, open flames, and incompatible materials. For long-term storage, consider refrigeration (2-8°C) under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.