Description

(4S)-4-Methyl-2-Oxo-[1,3,2]Dioxathiolane-4-Carboxylic Acid Methyl Ester is a high-purity chiral building block and synthetic intermediate of significant value in advanced organic synthesis. Its core value lies in its unique cyclic sulfate ester structure, which serves as a versatile electrophile for stereoselective transformations, enabling the efficient construction of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel agrochemicals where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug molecules, especially in the development of protease inhibitors and other therapeutics requiring specific stereochemistry.
• Agrochemical Synthesis: Used in the research and production of advanced, stereochemically defined pesticides and herbicides.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialized monomers or polymers with tailored properties.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic chemistry, particularly in reactions involving cyclic sulfates.

Basic Information

Product Name	(4S)-4-Methyl-2-Oxo-[1,3,2]Dioxathiolane-4-Carboxylic Acid Methyl Ester
CAS No.	356048-02-7
Molecular Formula	C6H8O6S
Molecular Weight	208.19 g/mol
Synonyms	Methyl (4S)-4-Methyl-2-oxo-1,3,2-dioxathiolane-4-carboxylate; (4S)-4-Methyl-2-oxo-1,3,2-dioxathiolane-4-carboxylic acid methyl ester; L-Glyceric acid cyclic sulfate methyl ester; (S)-(-)-2,3-O-Isopropylidene glyceric acid cyclic sulfate; (S)-4-Methyl-2-oxo-1,3,2-dioxathiolane-4-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our (4S)-4-Methyl-2-Oxo-[1,3,2]Dioxathiolane-4-Carboxylic Acid Methyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for sensitive synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.