Description

3,6,9,12,15-Pentaoxaheptadecane-1,17-Diyl Bis-Azide is a specialized bifunctional azide-terminated polyethylene glycol (PEG) derivative, serving as a critical click chemistry reagent. Its core value lies in enabling efficient, high-yield conjugation and polymer modification through copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions. This compound is essential for researchers and manufacturers in pharmaceuticals, advanced materials science, and bioconjugation who require reliable, high-purity linkers for constructing complex molecular architectures.

Application

• Bioconjugation and Protein Labeling: Used as a heterobifunctional crosslinker for attaching fluorophores, drugs, or other functional groups to biomolecules like antibodies and peptides.
• Polymer Chemistry & Material Science: A key monomer or chain extender for synthesizing functionalized PEG-based hydrogels, dendrimers, and smart materials with tailored properties.
• Pharmaceutical Development: Facilitates the creation of PEGylated drug conjugates and prodrugs to improve solubility, stability, and pharmacokinetic profiles of active pharmaceutical ingredients (APIs).
• Surface Functionalization: Enables the modification of nanoparticles, sensors, and diagnostic devices with bio-recognition elements or other functional coatings.
• Ligand Discovery & Chemical Biology: Employed in combinatorial library synthesis and activity-based protein profiling (ABPP) to discover new bioactive compounds.
• Diagnostic Reagent Synthesis: Used in the production of contrast agents, imaging probes, and components for diagnostic assays.

Basic Information

Product Name	3,6,9,12,15-Pentaoxaheptadecane-1,17-Diyl Bis-Azide
CAS No.	356046-26-9
Molecular Formula	C12H22N6O5
Molecular Weight	330.35 g/mol
Synonyms	1,17-Diazido-3,6,9,12,15-pentaoxaheptadecane; Bis-Azido-PEG5; Azido-PEG5-azide; α,ω-Diazido-pentaethylene glycol; PEG5 Bis-Azide; 1,11-Bis-azido-3,6,9-trioxaundecane (common naming variant); Tetraethylene glycol diazide; 2,2'-(Ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl) diazide (systematic)
EINECS	Contact for details

Quality Control

Our 3,6,9,12,15-Pentaoxaheptadecane-1,17-Diyl Bis-Azide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and FT-IR, to ensure high purity and consistent performance for sensitive click chemistry applications. Certificates of Analysis (COA) with detailed specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at temperatures between 2°C and 8°C (refrigerated) for long-term stability. This compound is strictly light-sensitive and should be handled under inert atmosphere when possible to prevent degradation. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.