Description

2-Propenoicacid,3-Amino-2-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-,Methyl is a specialized, high-purity amino acid derivative designed for advanced chemical synthesis. This compound is valued for its role as a key protected building block, enabling the precise construction of complex molecules in pharmaceutical and bioconjugate research. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for the development of novel therapeutics and diagnostic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of peptide mimetics and targeted drug candidates.
• Bioconjugation Chemistry: Used for the site-specific modification of proteins, antibodies, and other biomolecules.
• Proteomics Research: Serves as a reagent for labeling and cross-linking studies in biochemical assays.
• Solid-Phase Peptide Synthesis (SPPS): Employed as a protected amino acid derivative for the automated synthesis of custom peptides.
• Linker Molecule Development: Integral in creating cleavable or stable linkers for antibody-drug conjugates (ADCs).
• Chemical Biology Tool: Facilitates the study of protein function and interaction through selective chemical tagging.

Basic Information

Product Name	2-Propenoicacid,3-Amino-2-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-,Methyl
CAS No.	355377-13-8
Molecular Formula	C10H16N2O4
Molecular Weight	228.25 g/mol
Synonyms	Methyl 3-Amino-2-[(tert-butoxycarbonyl)amino]acrylate; Methyl 2-((tert-Butoxycarbonyl)amino)-3-aminoprop-2-enoate; Boc-Dap(OMe)-OH; (2E)-Methyl 3-amino-2-{[(2-methylpropan-2-yl)oxycarbonyl]amino}prop-2-enoate; 2-Propenoic acid, 3-amino-2-[[(1,1-dimethylethoxy)carbonyl]amino]-, methyl ester; Methyl (2E)-3-amino-2-(tert-butoxycarbonylamino)acrylate; Boc-Dap(Methyl Ester)-OH
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all critical parameters are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.