Description

2,3-Dichloro-4-Methylphenylboronic Acid is a versatile organoboron compound, specifically a substituted phenylboronic acid, that serves as a critical building block in modern synthetic chemistry. Its primary value lies in its role as a key coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex biaryl motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where its substituted aromatic structure contributes to biological activity.
• Material Science: Serves as a monomer or building block for creating specialized polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for methodology development and exploring new chemical spaces via cross-coupling chemistry.
• Ligand Synthesis: Utilized in the preparation of sophisticated ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2,3-Dichloro-4-Methylphenylboronic Acid
CAS No.	352535-95-6
Molecular Formula	C7H7BCl2O2
Molecular Weight	204.85 g/mol
Synonyms	(2,3-Dichloro-4-methylphenyl)boronic acid; 2,3-Dichloro-p-tolylboronic acid; 2,3-Dichloro-4-methylbenzeneboronic acid; B-(2,3-Dichloro-4-methylphenyl)boronic acid; 352535-95-6; 2,3-Dichloro-4-methylphenyl-Boronic Acid
EINECS	Contact for details

Quality Control

Our 2,3-Dichloro-4-Methylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive coupling reactions. Certificates of Analysis (COA) documenting purity, assay, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.