Description

4-(Trifluoromethyl)Umbelliferyl Oleate is a specialized fluorinated umbelliferone derivative ester, synthesized for advanced biochemical and diagnostic applications. This compound is valued for its role as a highly sensitive fluorogenic substrate for detecting specific enzymatic activity, particularly lipases and esterases. It is essential for researchers and manufacturers in the fields of diagnostic assay development, enzyme kinetics studies, and high-throughput screening within pharmaceutical and biotechnology sectors.

Application

• Fluorogenic Substrate for Lipase/Cholesterol Esterase: A key reagent in clinical diagnostic kits for measuring pancreatic lipase and other esterase activities in serum.
• Biochemical Research: Used in enzyme kinetics and inhibition studies to investigate lipolytic enzyme mechanisms.
• Diagnostic Manufacturing: Incorporated into the production of standardized calibrators and controls for automated clinical chemistry analyzers.
• High-Throughput Screening (HTS): Employed in pharmaceutical R&D for identifying and characterizing novel lipase inhibitors or activators.
• Food & Beverage Analysis: Potential use in assays for monitoring lipid degradation or enzyme activity in quality control processes.

Basic Information

Product Name	4-(Trifluoromethyl)Umbelliferyl Oleate
CAS No.	352525-07-6
Molecular Formula	C29H39F3O5
Molecular Weight	524.62 g/mol
Synonyms	4-Trifluoromethylumbelliferyl oleate; 4-Methylumbelliferyl oleate, 7-(trifluoromethyl)-; 7-Hydroxy-4-(trifluoromethyl)-2H-1-benzopyran-2-one oleate ester; Umbelliferyl oleate, 4-trifluoromethyl-; 4-TFMU oleate; Cholesterol esterase substrate; Lipase fluorogenic substrate; 4-Trifluoromethyl-7-oleoyloxycoumarin
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethyl)Umbelliferyl Oleate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for diagnostic and research applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. The product is light-sensitive and should be handled under appropriate conditions to prevent degradation. For long-term storage, consider storage under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	95.0 - 105.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.