Description

2,3,4,6-Tetrakis-o-(Trimethylsilyl)-α-D-Glucopyranosyl Iodide is a highly functionalized carbohydrate derivative, specifically a per-silylated glycosyl iodide. This compound serves as a key glycosylation donor in synthetic organic chemistry, enabling the stereoselective construction of complex oligosaccharides and glycoconjugates. It is an essential building block for researchers and manufacturers in pharmaceutical development, particularly for the synthesis of novel therapeutics, prodrugs, and diagnostic agents.

Application

• Glycosylation Reactions: As a critical donor molecule for the stereoselective synthesis of O-glycosidic linkages in oligosaccharides.
• Pharmaceutical Intermediates: For the production of complex carbohydrate-based active pharmaceutical ingredients (APIs) and prodrugs.
• Glycoconjugate Synthesis: Building block for creating glycopeptides, glycolipids, and other biologically relevant conjugates for drug discovery.
• Carbohydrate Chemistry Research: A versatile reagent in academic and industrial R&D for exploring new synthetic methodologies and carbohydrate structures.
• Diagnostic Agent Development: Used in the synthesis of labeled sugars or carbohydrate probes for imaging and diagnostic applications.
• Material Science: Potential precursor for synthesizing specialized carbohydrate-based polymers or surface modifiers.

Basic Information

Product Name	2,3,4,6-Tetrakis-o-(Trimethylsilyl)-α-D-Glucopyranosyl Iodide
CAS No.	352432-46-3
Molecular Formula	C18H41IO5Si4
Molecular Weight	609.75 g/mol
Synonyms	Per-O-trimethylsilyl-α-D-glucopyranosyl Iodide; 2,3,4,6-Tetra-O-(trimethylsilyl)-α-D-glucopyranosyl Iodide; α-D-Glucopyranosyl Iodide, 2,3,4,6-Tetrakis-O-(trimethylsilyl)-; 1-Iodo-2,3,4,6-tetra-O-trimethylsilyl-α-D-glucopyranose; TMS-Protected Glucosyl Iodide; α-D-Glucosyl Iodide Tetra-TMS Ether
EINECS	Contact for details

Quality Control

Every batch of 2,3,4,6-Tetrakis-o-(Trimethylsilyl)-α-D-Glucopyranosyl Iodide is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and lot-to-lot consistency, critical for sensitive glycosylation chemistry. A detailed Certificate of Analysis (COA) with specifications for assay, purity (by HPLC/NMR), and moisture content is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) due to its moisture-sensitive and light-sensitive nature. Allow the sealed container to reach room temperature before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.